Garfunkel and Oates heading to the Varsity Theater in Minneapolis

The women behind the musical-comedy duo Garfunkel and Oates don't look like troublemakers.

Kate Micucci, with her ukulele and doe-eyed reactions to the chaos around her, made her the ideal candidate to play a fragile geek on "The Big Bang Theory," so intimidated by big-hearted Raj that she climbed out a bathroom window in the middle of a date. Guitar player Riki Lindhome, who had a recurring role on "Gilmore Girls," exudes a Midwest-bred wholesomeness straight out of "Little House on the Prairie."

But it's those innocent first impressions that allow them to get away with comic murder.

On their IFC self-titled series as well as on a tour that brings them to Minneapolis on Friday, the longtime friends perform peppy, poppy numbers (that have titles like "Sex With Ducks," "Gay Boyfriend" and "This Party Took a Turn for the Douche") with "Sesame Street"-like enthusiasm — and lyrics that would make Grover's hair fall out.

We spoke to the red-hot pair by phone from their apartments in Los Angeles.  Read more...